Antioxidants and Anti-inflammatories

Alpha Lipoic Acid

INCI: Thioctic Acid

Alpha lipoic acid (ALA) is one of the most powerful anti-aging, antioxidant, anti-inflammatories available. ALA is called “the universal antioxidant” because it is both fat- and water-soluble. This means that ALA is easily absorbed through the lipid layers of the skin allowing it to neutralize free radicals in the cell membrane. Its antioxidant capacity is 400% more powerful than Vitamin C and E combined. ALA can reduce the appearance of pores, impart a healthy radiance to the skin, decrease the appearance of lines and wrinkles, and it has the capacity to regulate the production of nitric oxide, which increases blood flow to the skin.

Cell-communicating Ingredients 

Skinmimics®

INCI: Ceramide EOP; Ceramide EOS; Ceramide NP; Ceramide NS; Ceramide AP; Caprooyl Phytospingosine; Caprooyl Sphingosine; Ceteareth-25; Glycerin; Cetyl Alcohol; Behenic Acid; Cholesterol

Skinmimics® is a high-tech Ceramide complex that provides skin protection, prevention and regeneration. It is a skin-identical composition made up of specific long-chain ceramides, vegetable derived cholesterol and free fatty acid. This composition is combined with unique signaling molecules (Sphingokines®).

In vitro and in vivo studies have shown that Skinmimics displays a 3-in-1 benefit, especially on mature skin. It could be shown that Skinmimics significantly replenishes skin’s own protective barrier. Furthermore, this active is able to revitalize normal to dry skin by improving the skin's epidermal moisturizing system.

OceanDerMX® BALANCE & BRIGHTEN

INCI: Algae extract (New Zealand native red seaweed), Cyathea medullaris leaf extract (New Zealand native black fern), Centella asiatica leaf extract (Gotu Kola), Glycyrrhiza glabra root extract (Licorice root), Gluconolactone, Calcium gluconate, Potassium sorbate

New Zealand native Red seaweed inhibits the tyrosinase enzyme, decreasing hyperpigmentation. It consists of 8 sugar molecules that mimic the skin's Glycosaminoglycans (GAGs) that are able to bind to the skin's receptors, causing the delivery of bioactive ingredients directly to the skin cells and helping to increase the flexibility of the skin.

New Zealand native Fern Meristems add moisture to the skin and helps to tighten the skin immediately. It is also effective as an anti-oxidant and protects the skin from pollution.

Centella asiatica extract helps brighten the skin, reduce irritation, redness and inflammation of the skin. In addition it increases cell production and collagen synthesis, and is a rich source of amino acids. 

Studies show it effectively diminishes blemishes and hyperpigmentation in only 7 days. 

Niacinamide

Also known as Vitamin B3 and Nicotinamide, it is a multipurpose ingredient that acts as an anti-inflammatory and antioxidant that assists in several skin concerns. In addition to promoting repair mechanisms and reinforcing the protective skin barrier, it regulates oil production, stimulates collagen and ceramide production, minimizes fine lines and wrinkles and fades hyperpigmentation.

Lecithin

Consisting of phospholipids, the building materials of cell membranes. It acts as an antioxidant, humectant, emollient and softening agent and assists active substances penetrate deeper into the skin making them more effective. It also acts as a humectant and its moisturizing properties help to keep the skin hydrated while protecting the skin from external aggressors.

Microbiome Regulating Ingredients 

Ecoskin®

INCI: Alpha-glucan oligosaccharide; Polymnia sonchifolia (Yacón) root juice; Maltodextrin; Lactobacillus

Ecoskin® is a pre/probiotic complex that acts as a radiance promoter. It made of the prebiotic ingredients α-glucooligosaccharides (GOS), fructooligosaccharides (FOS) and lactobacillus probiotic bacteria, (L. casei and L, acidophilus). It promotes the balance of the skin microbiota by acting as a substrate for commensal bacteria and strengthening the natural defense of the skin. 

Evaluated against placebo, on a panel of subjects with very dry skin, Ecoskin® enhances the skin’s radiance by reducing the average depth of the micro-furrows, restructuring the skin, while nourishing it and reducing feelings of discomfort. 

BIOME Oléoactif®

INCI: Simmondsia Chinensis (Jojoba) Seed Oil (and) Avena Sativa (Oat) Kernel Oil (and) Bacillus Ferment

Is a fermentation-derived active that is produced by capturing rare lipids from a wild extremophile microorganism then offering them to the skin and its microbiota. It acts as a prebiotic and can regulate the skin microbiota and reinforce the skin barrier function. It creates a holistic system that promotes healthy, youthful & beautiful skin. BIOME Oléoactif® balances the skin microbiota and maintains the integrity of the epidermal barrier. It exhibits moisturizing, restructuring, soothing and emollient properties. It has a unique composition of innovative active molecules.

 In vitro test on skin as well as a clinical test on cutaneous microbiota (16S rDNA sequencing) showed that proved BIOME Oléoactif® preserves the bacterial diversity and microbiota global composition of healthy skin, thus balancing and protecting the critical microbiome ecosystem.

Humectants (hydrators and moisture retainers) 

Cosphaderm® Sodium Hyaluronate low 5

INCI: Sodium Hyaluronate

Containing the lowest molecular size of the salt form of hyaluronic acid, it is able to penetrate deep into the dermis where it can act as a humectant, conditioning agent and anti-inflammatory to provide deep penetrating and long-lasting moisturization. It is a mucopolysaccharide of 5-3 kDa that provides excellent moisturizing and skincare properties including reducing wrinkle depth and increasing elasticity.

Cosphaderm® Sodium Hyaluronate low can reduce the depth of wrinkles by approximately 11 % after 60 days. The long-term humidification of skin will be increased by approximately 16 % and the skin elasticity by approximately 13 %.

Unimoist U-125 G

INCI: Glycerin, Urea, Saccharide Hydrolysate, Magnesium Aspartate, Glycine, Alanine, Creatine

Comprised of several essential amino acids, urea and magnesium, this complex acts as a moisturizing agent. It is a complete combination of active substances which are very similar to those of the natural moisturizing factor (NMF) naturally present within the skin. It brings about a normalization of the water content of the epidermis, thus producing an improvement in suppleness and elasticity and at the same time preventing premature ageing of the skin.

Lactic acid

A gentle chemical exfoliant in the group known as alpha-hydroxy acids or AHA’s, which work to remove dead skin cells and hydrate the skin. It helps to minimize acne breakouts, brighten the skin and reduce the appearance of wrinkles and fine lines.

Leucidal® Liquid

INCI: Leuconostoc/Radish Root Ferment Filtrate

An antimicrobial peptide produced from the fermentation of lactic acid bacteria Leuconostoc Kimichii. It is a moisturizing ingredient and is used as a natural preservative in all Eunoia products as it acidifies its environment and through the production of an antimicrobial peptide that it produces as a defense mechanism. It retains the effectiveness of the formula and allows for the elimination of traditional preservatives that may disrupt the microbiome and cause sensitivity.

A skin moisturization study was performed with results showing the addition of the leucidial provided a 10% increase in moisturization.

Brighteners (pigment reducers)

FLORANT-FG

INCI: Aqua, Butylene Glycol, Saccharomyces/Panax Ginseng Flower Ferment Extract

Provides a skin tone evening and brightening effect by inhibiting the expression for inflammation. Saponins are the major contributors to the anti-inflammation activity. Saccharomyces extract is a fermented ingredient produced from yeast rich in essential amino acids and minerals and beta-glucan. It works by encouraging cell turnover, improving the appearance of fine lines. The result is brighter, more moisturized and soothed skin. Fermented Ginseng Root has anti-aging properties as it helps to sustain skin elasticity and has antioxidant properties, protecting skin against free radical damage and decreasing pigmentation.

Florant-FG inhibits the production of pro-inflammatory cytokines expression of TNF-α and PGE2 . In addition, after 3 weeks of use, the melanin index (measurement of pigmentation) decreased from 90% to 70%.

Emollients (skin softeners) 

Coco Caprylate

Is a vegetable ingredient obtained from coconuts that presents a high level of biocompatibility with skin and therefore has the ability to penetrate deep and help the skin to repair itself. It acts as an emollient and provides skin with incredible softness.